Functional Interactions Among Trabecular, Cortical, and Compositional Bone Traits Contribute to Genetic Variation in Mechanical Functionality of Adult Recombinant Inbred Mouse Vertebrae
نویسندگان
چکیده
Functional Interactions Among Trabecular, Cortical, and Compositional Bone Traits Contribute to Genetic Variation in Mechanical Functionality of Adult Recombinant Inbred Mouse Vertebrae Steven M. Tommasini1, Bin Hu2, Joseph H. Nadeau3, Karl J. Jepsen2 1Dept. of Biomedical Engineering, CCNY/CUNY Graduate Center, New York, NY; 2Dept. of Orthopaedics, Mt. Sinai School of Medicine, New York, NY; 3Dept. of Genetics, Case Western Reserve University, Cleveland, OH [email protected]
منابع مشابه
Genetic variations that regulate bone morphology in the male mouse skeleton do not define its susceptibility to mechanical unloading.
Genetics can substantially influence bone morphology and may define the skeleton's response to mechanical unloading. Recent data indicated that disuse produces different site-specific responses in the skeleton of genetically distinct adult female C3H/HeJ (C3H) and BALB/cByJ (BALB) mice; while disuse BALB mice had significantly less bone than age-matched controls in the distal and diaphyseal fem...
متن کاملGenetic relationships between obesity and osteoporosis in LGXSM recombinant inbred mice.
Obesity and osteoporosis affect millions of Americans. While phenotypically, obesity is negatively correlated with fracture risk, research on a genetic basis for this relationship is lacking. We used males and females from 16 LGXSM recombinant inbred (RI) mouse strains to investigate the genetically mediated relationship between obesity and osteoporosis-related traits. First, heritabilities wer...
متن کاملGenetic diversity of Iranian rice recombinant inbred lines at the reproductive stage in normal conditions and salinity
Salinity is an important limiting factor in the production of more plants, including rice. Due to the limited amount of cultivated area, identification of tolerant genotypes to environmental stresses and especially salinity is very important. The aim of this study was to investigate the genetic diversity among 114 recombinant lines derived from the intersection of local Tarom × Khazar cultivars...
متن کاملGenetic Diversity and Relationships of Agronomic Characters in Wheat Recombinant Inbred Lines
Objective: Wheat is the most important crop in Iran. Self sufficiency in wheat production is one of the economic and food safety policies in the country. In spite of the efforts which have been made in this area, the mean of wheat yield in Iran is less than its world average. Methods: In order to identifying of the high yielding wheat lines with optimal characteristics and to determine the trai...
متن کاملGenetic Diversity and Relationships of Agronomic Characters in Wheat Recombinant Inbred Lines
Objective: Wheat is the most important crop in Iran. Self sufficiency in wheat production is one of the economic and food safety policies in the country. In spite of the efforts which have been made in this area, the mean of wheat yield in Iran is less than its world average. Methods: In order to identifying of the high yielding wheat lines with optimal characteristics and to determine the trai...
متن کامل